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Neil Simon's Lost in Yonkers play, set in 1942 Yonkers, New York, is a  human comedy about two young brothers, Jay and Arty , who are forced by cirumstances to live with their austere and demanding grandmother, their loving high-spirited and childlike Aunt Bella and their tough-talking gangster Uncle Louie. While firmly anchored in time and place, the strength of this play lies in its larger view of how human differences, pain and lots of humour go into the making of a family. It is an ageless and universal theme which Neil Simon pursued with great dramatic insight to win a Pulitzer Prize.